A :: B :: C :: D :: E :: F :: G :: H :: I :: J :: K :: L :: M :: N :: O :: P :: Q :: R :: S :: T :: U :: V :: W :: X :: Y :: Z :: Extras :: Links :: perso ::

   WADSWORTH (HORNER-EMMONS) olefination



mechanism:

 

remarks:

  • The strength of the O–P bond is the driving force of the reaction.
  • Phosphonates are prepared according to Michaelis-Arbuzov and Michaelis-Becker reactions.
  • see also:  Wittig olefination.


references:

J. Org. Chem. 2007, 72, 6263.
Synlett 2007, 571.
Org. Lett. 2007, 9, 1001.
Tetrahedron Lett. 2006, 47, 6527.
J. Org. Chem. 2006, 71, 6135.
J. Am. Chem. Soc. 2006, 128, 5340.
Org. Lett. 2005, 7, 4281.
Tetrahedron Lett. 2004, 45, 5519.